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A notable reduction in PSA was also associated with lycopene alone ( P = 0.009)

141 Notably, it has been reported that the first extracellular domains of claudin-2 and claudin-4 are a key determinant of paracellular charge selectivity and barrier function, but these domains are not involved in the formation of tight junction strands

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Rec Nat Prod 5:158175 Gulcin I, Beydemir S, Topal F, Gagua N, Bakuridze A, Bayram R, Gepdiremen A (2012) Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst